Why not include a hike in your brewery tour?
This tour covers locations to the South and West of Downtown Asheville. It will take the better part of the day if you choose to include the hike to the top of Looking Glass Rock, but is well worth it, as Looking Glass affords one of the best views of the Pisgah. I would suggest starting at Ecusta Brewing right when they open. From there, drive up to see the falls, which are roadside. From there, turn around and turn right towards the fish hatchery. The trailhead will be on your right in about 1/2 mile.
Finish the day with a meal at Sierra Nevada Brewing.